Blueberry juice improves total and LDL cholesterol and psychological wellbeing in adults
In a 20-day randomized controlled trial, 60 mL/day of blueberry juice significantly reduced total cholesterol from 4.36 to 3.79 mmol/L and LDL cholesterol from 2.71 to 2.23 mmol/L compared to placebo, which showed increases. Psychological wellbeing indices (Beck Depression Inventory, State Trait Anxiety Inventory, COOP WONCA) also improved significantly in the blueberry group.
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Blueberry juice improves total and LDL cholesterol and psychological wellbeing in adults The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 42/100 (low).
The Claim
Blueberry juice improves total and LDL cholesterol and psychological wellbeing in adults
This conclusion is most relevant to: 45 adults (randomly assigned to three arms).
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Effects of Montmorency Tart Cherry and Blueberry Juice on Cardiometabolic and Other Health-Related Outcomes: A Three-Arm Placebo Randomized Controlled Trial. (International journal of environmental research and public health, 2022) —
How It Works
The proposed biological pathway:
- ▸Blueberry polyphenols may reduce cholesterol absorption or increase excretion
- ▸Anthocyanins in blueberries may improve endothelial function and reduce inflammation
- ▸Improved lipid profile and reduced oxidative stress may enhance mood and psychological wellbeing
- ▸Result: Lower total and LDL cholesterol and improved psychological wellbeing
Who Might Benefit
Evidence fit by population:
- ▸45 adults (randomly assigned to three arms)
Recommended Dose
60 mL per day
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Small sample size (n=45) limits generalizability
- ▸Short intervention period (20 days) may not reflect long-term effects
- ▸No significant effect on primary outcome (systolic blood pressure) reduces overall impact
Frequently Asked Questions
Did tart cherry juice also improve cholesterol or psychological wellbeing?▼
No, the abstract reports significant improvements only for the blueberry juice arm compared to placebo; tart cherry juice did not show statistically significant effects on these outcomes.
What was the primary outcome of this study?▼
The primary outcome was systolic blood pressure, which showed no statistically significant difference between groups.
How long did participants take the juice?▼
Participants consumed 60 mL of juice per day for 20 days.
Were there any changes in sleep efficacy?▼
Sleep efficacy was measured as a secondary outcome, but the abstract does not report any significant findings for it.
References
- 1.Sinclair J, Bottoms L, Dillon S, Allan R, Shadwell G, Butters B. “Effects of Montmorency Tart Cherry and Blueberry Juice on Cardiometabolic and Other Health-Related Outcomes: A Three-Arm Placebo Randomized Controlled Trial..” International journal of environmental research and public health, 2022. PMID: 35564709 DOI: 10.3390/ijerph19095317