Supplements

Fenavari (combined standardized extract of fenugreek and shatavari) significantly reduces menopausal symptoms and improves sleep quality in women aged 40-60 years

In a randomized, double-blind, placebo-controlled trial, 138 women with menopausal symptoms received Fenavari 300 mg, Fenavari 500 mg, or placebo daily for 84 days. Both doses significantly reduced Menopause Rating Scale (MRS) total scores from Day 14 onward, with the 500 mg dose showing greater effects (MRS change: -10.40 vs -8.26 for 300 mg vs -4.09 for placebo). Significant improvements were also observed in sleep quality, anxiety, mood, and hormonal parameters (increased estradiol, decreased FSH).

1 min readUpdated Aug 5, 20261 RCTsView structured evidence →
Evidence Score44/100
Human RCT★★☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism★★★★★
Safety★★★★
Confidencelow

This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.

Fenavari (combined standardized extract of fenugreek and shatavari) significantly reduces menopausal symptoms and improves sleep quality in women aged 40-60 years The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 44/100 (low).

The Claim

Fenavari (combined standardized extract of fenugreek and shatavari) significantly reduces menopausal symptoms and improves sleep quality in women aged 40-60 years

This conclusion is most relevant to: Women aged 40-60 years with menopausal symptoms.

What the Research Shows

The conclusion draws on 1 linked study. Highlights from the cited literature:

  • Dose-Dependent Efficacy of a Combined Standardized Extract of Fenugreek and Shatavari on Menopausal Symptoms: A Randomized, Double-Blind, Parallel, Placebo-Controlled Study. (Women's health reports (New Rochelle, N.Y.), 2026) —

How It Works

The proposed biological pathway:

  • Fenavari contains phytoestrogens from fenugreek and shatavari
  • Phytoestrogens bind to estrogen receptors, mimicking estrogen action
  • This leads to increased serum estradiol and reduced FSH levels
  • Result: alleviation of menopausal symptoms and improved sleep, mood, and anxiety

Who Might Benefit

Evidence fit by population:

  • Women aged 40-60 years with menopausal symptoms

Limitations & Caveats

Important context when interpreting this evidence:

  • Study duration was only 84 days; long-term efficacy and safety not assessed
  • No comparison with hormone replacement therapy or other standard treatments
  • Potential industry bias as the study may have been funded by the manufacturer
  • No data on adherence or dropout reasons beyond completion rates

Frequently Asked Questions

What is Fenavari?

Fenavari is a novel formulation combining standardized extracts of Asparagus racemosus (shatavari) and Trigonella foenum-graecum (fenugreek), used as a nonhormonal option for menopausal symptom relief.

How quickly does Fenavari work for menopausal symptoms?

Significant reductions in Menopause Rating Scale scores were observed from Day 14 of treatment, with continued improvement through Day 84.

Does Fenavari improve sleep quality?

Yes, the study reported significant improvements in sleep quality as measured by the Pittsburgh Sleep Quality Index by Day 84 compared to placebo.

What dose of Fenavari is recommended?

The study tested 300 mg and 500 mg daily; the 500 mg dose showed earlier and greater effects, suggesting it may be more effective.

References

  1. 1.Kashinath RN, Bhat VV, Morde A, Joshua L, Thomas JV. “Dose-Dependent Efficacy of a Combined Standardized Extract of Fenugreek and Shatavari on Menopausal Symptoms: A Randomized, Double-Blind, Parallel, Placebo-Controlled Study..” Women's health reports (New Rochelle, N.Y.), 2026. PMID: 42539366 DOI: 10.1177/26884844261465161
Disclaimer: This article is auto-generated from structured research data for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.