Montmorency tart cherry powder at 500 mg daily does not improve sleep or inflammation outcomes in individuals with overweight or obesity
In a randomized controlled crossover trial of 34 individuals with overweight or obesity and sleep issues, 500 mg of Montmorency tart cherry powder taken one hour before bed for 14 days showed no significant effects on sleep outcomes (total sleep time, deep and REM sleep, nap duration, nocturnal sleep duration) or inflammatory markers (CRP, TNF-α, IL-6, IL-8, IL-10, IL-17A) compared to placebo (p > 0.05 for all). The study suggests that higher doses than currently recommended may be needed for this population.
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Montmorency tart cherry powder at 500 mg daily does not improve sleep or inflammation outcomes in individuals with overweight or obesity The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 23/100 (low).
The Claim
Montmorency tart cherry powder at 500 mg daily does not improve sleep or inflammation outcomes in individuals with overweight or obesity
This conclusion is most relevant to: Individuals with sleep issues and overweight or obesity (mean BMI 32.1 ± 7.0 kg/m²).
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or Obesity. (Nutrients, 2024) —
How It Works
The proposed biological pathway:
- ▸MTC supplementation taken before bed
- ▸Expected to improve sleep via melatonin or anti-inflammatory pathways
- ▸Measured sleep and inflammation outcomes
- ▸No significant improvements observed
Who Might Benefit
Evidence fit by population:
- ▸Individuals with sleep issues and overweight or obesity (mean BMI 32.1 ± 7.0 kg/m²)
Recommended Dose
500 mg daily (commonly used dose; authors suggest higher doses may be needed)
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Small sample size (n=34)
- ▸Short intervention duration (14 days)
- ▸Dose may be insufficient for overweight/obese population
Frequently Asked Questions
Does Montmorency tart cherry powder improve sleep in overweight or obese individuals?▼
No, this study found no significant improvement in sleep outcomes with 500 mg daily for 14 days.
What dose of tart cherry powder was tested?▼
500 mg of Montmorency tart cherry powder capsules taken one hour before bed.
How long did the study last?▼
Participants took the supplement or placebo for 14 days in a crossover design.
What were the main outcomes measured?▼
Sleep outcomes (total sleep time, deep sleep, REM sleep, nap duration, subjective sleep quality) and inflammatory markers (CRP, TNF-α, IL-6, IL-8, IL-10, IL-17A).
References
- 1.Tucker RM, Kim N, Gurzell E, Mathi S, Chavva S, Senthilkumar D, Bartunek O, Fenton KC, Herndon-Fenton SJ, Cardino VN, Cooney GM, Young S, Fenton JI. “Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or Obesity..” Nutrients, 2024. PMID: 39683518 DOI: 10.3390/nu16234125