Multi-herb formula (VL-G-A57) and ashwagandha (VL-G-E12) improve sleep quality in stressed adults
In a 60-day RCT, both VL-G-A57 (Rhodiola, holy basil, Schisandra chinensis) and VL-G-E12 (full-spectrum ashwagandha) significantly improved sleep quality as measured by PSQI compared to placebo (VL-G-A57: p=0.0008; VL-G-E12: p<0.0001). Restorative sleep also improved significantly in both groups (p<0.0001).
This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.
Multi-herb formula (VL-G-A57) and ashwagandha (VL-G-E12) improve sleep quality in stressed adults The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 42/100 (low).
The Claim
Multi-herb formula (VL-G-A57) and ashwagandha (VL-G-E12) improve sleep quality in stressed adults
This conclusion is most relevant to: Adults aged 18-65 years with high stress, BMI 18-29.9 kg/m².
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study. (Trials, 2026) —
How It Works
The proposed biological pathway:
- ▸Adaptogens modulate HPA axis activity
- ▸Reduction in cortisol and stress response
- ▸Improved regulation of sleep-wake cycle
- ▸Result: Enhanced sleep quality and restorative sleep
Who Might Benefit
Evidence fit by population:
- ▸Adults aged 18-65 years with high stress, BMI 18-29.9 kg/m²
Recommended Dose
N/A
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Dose and exact formulation details not provided in abstract
- ▸Mechanism of action not directly measured (e.g., cortisol levels not reported)
- ▸Short duration (60 days) limits long-term efficacy assessment
Frequently Asked Questions
What is VL-G-A57?▼
VL-G-A57 is a multi-herb formula containing Rhodiola, holy basil, and Schisandra chinensis, tested as an adaptogen for stress and sleep.
How was sleep quality measured in this study?▼
Sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI) and the Restorative Sleep Questionnaire-Weekly (RSQ-W).
Did both supplements improve sleep?▼
Yes, both VL-G-A57 and VL-G-E12 (ashwagandha) significantly improved PSQI scores and restorative sleep compared to placebo.
Who was eligible for this study?▼
Participants were adults aged 18-65 years with high stress and a BMI between 18 and 29.9 kg/m².
References
- 1.McKinney E, Stewart J, Kewalramani R, Singh S. “Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study..” Trials, 2026. PMID: 41656269 DOI: 10.1186/s13063-026-09495-9