Nurse-led algorithm-based early mobilization protocol reduces post-intensive care syndrome in cardiac surgery ICU patients
In a randomized controlled trial of 38 cardiac surgery ICU patients, a nurse-led algorithm-based early mobilization protocol significantly reduced PICS scores (Z = -3.83, P < .001), anxiety and depression (Z = -3.52, P < .001), and improved sleep quality (Z = -3.83, P < .001) compared to usual care. No mobilization-related adverse events occurred.
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Nurse-led algorithm-based early mobilization protocol reduces post-intensive care syndrome in cardiac surgery ICU patients The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 44/100 (low).
The Claim
Nurse-led algorithm-based early mobilization protocol reduces post-intensive care syndrome in cardiac surgery ICU patients
This conclusion is most relevant to: Adult patients following cardiac surgery in a Korean tertiary hospital ICU.
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Nurse-Led Algorithm-Based Early Mobilization Protocol for Reducing Post-Intensive Care Syndrome in Intensive Care Unit Patients: A Randomized Controlled Trial. (The Journal of cardiovascular nursing, 2026) —
How It Works
The proposed biological pathway:
- ▸Early mobilization reduces physical deconditioning and ICU-acquired weakness
- ▸Reduced physical impairment may lower risk of cognitive and psychological dysfunction
- ▸Structured protocol may reduce anxiety and depression through increased patient engagement and autonomy
- ▸Improved sleep quality and nursing satisfaction due to standardized care and patient interaction
Who Might Benefit
Evidence fit by population:
- ▸Adult patients following cardiac surgery in a Korean tertiary hospital ICU
Recommended Dose
N/A
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Small sample size (n=38) limits generalizability
- ▸Single-center study in a Korean tertiary hospital may not be representative of other settings
- ▸No long-term follow-up to assess sustainability of effects
- ▸Outcome assessors were not blinded (not explicitly stated)
Frequently Asked Questions
What is post-intensive care syndrome (PICS)?▼
PICS refers to new or worsening physical, cognitive, or mental health impairments that persist after critical illness and ICU stay.
How early can early mobilization start after cardiac surgery?▼
In this study, the protocol began 12 hours after ICU admission, suggesting that early mobilization can be safely initiated within the first day post-surgery.
Is nurse-led early mobilization safe for cardiac surgery patients?▼
Yes, this study reported no mobilization-related adverse events, indicating that a nurse-led algorithm-based protocol is safe in this population.
What outcomes were improved by the early mobilization protocol?▼
The protocol significantly reduced PICS scores, anxiety and depression, and improved sleep quality and nursing satisfaction compared to usual care.
References
- 1.Jeong Y, Lee H. “Nurse-Led Algorithm-Based Early Mobilization Protocol for Reducing Post-Intensive Care Syndrome in Intensive Care Unit Patients: A Randomized Controlled Trial..” The Journal of cardiovascular nursing, 2026. PMID: 42585547 DOI: 10.1097/JCN.0000000000001373