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Nurse-led family intervention (SCCIP-N) may reduce post-traumatic stress symptoms in families of children with cancer in China

This protocol describes a multicentre randomised controlled trial evaluating a nurse-led family-based psychosocial intervention (SCCIP-N) to reduce post-traumatic stress symptoms (PTSS) in families of paediatric cancer patients. The trial will enrol 110 families across Hunan and Xinjiang, with assessments at baseline and 1, 4, and 8 weeks post-intervention. Primary outcomes are PTSS in children and caregivers, with secondary outcomes including sleep quality and physiological measures.

1 min readUpdated Aug 22, 20261 RCTsView structured evidence →
Evidence Score42/100
Human RCT★★☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism★★★★★
Safety★★★★
Confidencelow

This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.

Nurse-led family intervention (SCCIP-N) may reduce post-traumatic stress symptoms in families of children with cancer in China The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 42/100 (low).

The Claim

Nurse-led family intervention (SCCIP-N) may reduce post-traumatic stress symptoms in families of children with cancer in China

This conclusion is most relevant to: 110 families of children with cancer in Hunan and Xinjiang, China.

What the Research Shows

The conclusion draws on 1 linked study. Highlights from the cited literature:

  • Multicentre randomised controlled trial of a nurse-led family intervention on post-traumatic stress symptoms in families of children with cancer in China: protocol for the SCCIP-N trial. (BMJ open, 2026) —

How It Works

The proposed biological pathway:

  • Family-based psychosocial intervention delivered by nurses
  • Targets post-traumatic stress symptoms and related psychological outcomes
  • Uses hybrid assessment including validated psychosocial measures and objective physiological monitoring
  • Expected to reduce PTSS and improve family functioning and sleep quality

Who Might Benefit

Evidence fit by population:

  • 110 families of children with cancer in Hunan and Xinjiang, China

Limitations & Caveats

Important context when interpreting this evidence:

  • This is a protocol paper; results are not yet available, so efficacy is not established
  • The trial is ongoing and may face recruitment or implementation challenges across diverse sites

Frequently Asked Questions

What is the SCCIP-N intervention?

SCCIP-N is a nurse-led family-based psychosocial intervention adapted from the Surviving Cancer Competently Intervention Programme (SCCIP), designed to reduce post-traumatic stress symptoms in families of children with cancer.

How many families are enrolled in the trial?

The trial will enrol 110 families across two sites in China (Hunan and Xinjiang).

What are the primary outcomes measured?

The primary outcome is post-traumatic stress symptoms (PTSS) in children and caregivers, assessed at baseline and at 1, 4, and 8 weeks post-intervention.

How is sleep quality measured in this study?

Sleep quality is a secondary outcome, measured using wearable devices that record total sleep time, sleep score, heart rate, and resting heart rate from primary caregivers.

References

  1. 1.Zeng X, Kong Y, Shi Y, Ye Y, Gu C. “Multicentre randomised controlled trial of a nurse-led family intervention on post-traumatic stress symptoms in families of children with cancer in China: protocol for the SCCIP-N trial..” BMJ open, 2026. PMID: 42624591 DOI: 10.1136/bmjopen-2026-119064
Disclaimer: This article is auto-generated from structured research data for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.