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Objective sleep parameters are associated with cognitive performance in euthymic bipolar disorder

In 40 euthymic individuals with bipolar disorder, longer assumed sleep duration was negatively associated with overall cognitive performance (β = -0.38, p = 0.011). Longer sleep onset latency was negatively associated with working memory (β = -0.41, p = 0.014) and processing speed (β = -0.38, p = 0.002), while greater wake time after sleep onset was negatively associated with verbal fluency (β = -0.39, p = 0.016).

1 min read•Updated Jul 7, 2026•0 RCTs•View structured evidence →
Evidence Score38/100
Human RCT☆☆☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism☆☆☆☆☆
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Confidencelow

This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.

Objective sleep parameters are associated with cognitive performance in euthymic bipolar disorder The current body of evidence comprises 1 study. EvidenceHub rates the overall confidence at 38/100 (low).

The Claim

Objective sleep parameters are associated with cognitive performance in euthymic bipolar disorder

This conclusion is most relevant to: 40 euthymic individuals with bipolar disorder.

What the Research Shows

The conclusion draws on 1 linked study. Highlights from the cited literature:

  • ▸Objective sleep parameters and cognitive performance in euthymic bipolar disorder: a cross-sectional 21-day actigraphy study. (International journal of bipolar disorders, 2026) —

How It Works

The proposed biological pathway:

  • ▸Sleep disturbances persist during euthymia in bipolar disorder
  • ▸Objective sleep parameters (duration, latency, continuity) are measured via actigraphy
  • ▸Cognitive performance is assessed using SCIP
  • ▸Longer sleep duration, longer sleep onset latency, and more wake after sleep onset are associated with worse cognitive performance

Who Might Benefit

Evidence fit by population:

  • ▸40 euthymic individuals with bipolar disorder

Limitations & Caveats

Important context when interpreting this evidence:

  • ▸Cross-sectional design prevents causal inference
  • ▸Small sample size (n=40) limits generalizability
  • ▸Exploratory nature with multiple comparisons; results require replication

References

  1. 1.Libourel C, Charron M, Martinot V, Carminati M, Etain B, Hennion V. “Objective sleep parameters and cognitive performance in euthymic bipolar disorder: a cross-sectional 21-day actigraphy study..” International journal of bipolar disorders, 2026. PMID: 42371207 DOI: 10.1186/s40345-026-00431-z
Disclaimer: This article is auto-generated from structured research data for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.