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Poor subjective sleep quality is common in tension-type headache and associated with depressive symptoms

The pooled prevalence of poor sleep quality (PSQI >5) in adults with tension-type headache was 67% (95% CI 53-79%). The mean PSQI score was 9.48, significantly higher than controls (mean difference 3.77, 95% CI 2.32-5.22), and correlated robustly with depression (r=0.51).

1 min readUpdated Jul 28, 20260 RCTs1 Meta-analysesView structured evidence →
Evidence Score49/100
Human RCT☆☆☆☆☆
Meta-analysis★★★☆☆
Mechanism★★★★★
Safety★★★★
Confidencelow

This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.

Poor subjective sleep quality is common in tension-type headache and associated with depressive symptoms The current body of evidence comprises 1 study and 1 meta-analysis. EvidenceHub rates the overall confidence at 49/100 (low).

The Claim

Poor subjective sleep quality is common in tension-type headache and associated with depressive symptoms

This conclusion is most relevant to: Adults with tension-type headache (TTH) from 27 observational studies.

What the Research Shows

The conclusion draws on 1 linked study. Highlights from the cited literature:

  • Sleep disturbances in tension-type headache: a systematic review and meta-analysis. (Journal of neurology, 2026) — The pooled prevalence of poor sleep quality (PSQI >5) in adults with tension-type headache was 67% (95% CI 53-79%). The mean PSQI score was 9.48, significantly higher than controls (mean difference 3.77, 95% CI 2.32-5.22), and correlated robustly with depression (r=0.51).

How It Works

The proposed biological pathway:

  • Tension-type headache is associated with central sensitization and pain processing abnormalities
  • Sleep disturbances may exacerbate pain sensitivity and headache frequency
  • Depressive symptoms are strongly correlated with poor sleep quality in TTH patients
  • Result: Bidirectional relationship between sleep disturbance and TTH, with depression as a key mediator

Who Might Benefit

Evidence fit by population:

  • Adults with tension-type headache (TTH) from 27 observational studies

Limitations & Caveats

Important context when interpreting this evidence:

  • High heterogeneity (I²=97%) across studies, partly explained by recruitment settings
  • Correlations with headache frequency and intensity were nominal and exploratory, not robust after multiple testing correction

Frequently Asked Questions

What percentage of people with tension-type headache have poor sleep quality?

The pooled prevalence is 67% based on PSQI scores, though estimates ranged from 53% to 79% across studies.

Is poor sleep quality in tension-type headache linked to depression?

Yes, the correlation between PSQI scores and depressive symptoms was strong (r=0.51) and statistically significant after correction for multiple testing.

Does sleep duration differ between TTH patients and controls?

No, mean sleep duration was 6.61 hours and did not differ significantly from non-headache controls.

What sleep disorders are common in tension-type headache?

Insomnia was reported in 37%, excessive daytime sleepiness in 13%, and high OSA risk or confirmed OSA in 26% of TTH patients.

References

  1. 1.Yuan L, Kulachai P, Wu QM, Zhang YX, Niu XY, Liang JT, Zheng H. “Sleep disturbances in tension-type headache: a systematic review and meta-analysis..” Journal of neurology, 2026. PMID: 42493638 DOI: 10.1007/s00415-026-14011-9
Disclaimer: This article is auto-generated from structured research data for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.