Unbalanced 24h movement behavior trajectories after acute stroke are associated with increased risk of poor functional recovery at 12 months
In a prospective longitudinal study of 298 stroke survivors, four distinct 24h movement behavior trajectories were identified. Compared to a balanced trajectory, the imbalance group (OR=5.237, 95%CI: 1.848-14.835) and the long-sleep, increased-sedentary, decreased-physical-activity group (OR=4.160, 95%CI: 1.589-10.891) had significantly higher odds of poor functional recovery at 12 months, after adjusting for multiple confounders.
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Unbalanced 24h movement behavior trajectories after acute stroke are associated with increased risk of poor functional recovery at 12 months The current body of evidence comprises 1 study. EvidenceHub rates the overall confidence at 34/100 (low).
The Claim
Unbalanced 24h movement behavior trajectories after acute stroke are associated with increased risk of poor functional recovery at 12 months
This conclusion is most relevant to: Stroke survivors (n=298) from five hospitals in Henan province, China.
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸24h movement behavior trajectory and functional recovery after acute stroke: a prospective study. (Archives of physical medicine and rehabilitation, 2026) —
How It Works
The proposed biological pathway:
- ▸Acute stroke disrupts normal 24h movement behavior patterns
- ▸Unbalanced trajectories (e.g., excessive sleep, increased sedentary time, reduced physical activity) may impair neuroplasticity and recovery
- ▸Poor movement behavior may exacerbate cardiovascular and metabolic risks, hindering functional recovery
- ▸Result: Increased odds of poor functional outcome at 12 months
Who Might Benefit
Evidence fit by population:
- ▸Stroke survivors (n=298) from five hospitals in Henan province, China
Recommended Dose
N/A
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Observational design cannot establish causality
- ▸Potential residual confounding despite adjustment for multiple factors
- ▸Sample limited to one region in China, limiting generalizability
- ▸Attrition (353 to 298) may introduce selection bias
Frequently Asked Questions
What are the four trajectories of 24h movement behavior identified in stroke survivors?▼
The abstract mentions four potential categories were identified, but the specific names are not listed. The two high-risk groups are '24h movement behavior imbalance' and 'long-SLP increased-SB decreased-PA'.
How was 24h movement behavior measured in this study?▼
The ActiGraph GT3X+ accelerometer was used to collect 24h movement behavior data at three time points: acute phase (T0), 3-month recovery phase (T1), and 6-month sequelae phase (T2).
What was the primary outcome and how was it assessed?▼
The primary outcome was functional recovery at 12 months post-stroke, assessed using the modified Rankin Scale (mRS).
What does the odds ratio of 5.237 for the imbalance group mean?▼
It means that stroke survivors in the 24h movement behavior imbalance group had 5.237 times the odds of poor functional recovery compared to the balanced group, after adjusting for confounders.
References
- 1.Dong X, Wei J, Yang F, Li C, Sun C, Liu Y. “24h movement behavior trajectory and functional recovery after acute stroke: a prospective study..” Archives of physical medicine and rehabilitation, 2026. PMID: 42542202 DOI: 10.1016/j.apmr.2026.07.025