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A personalized six-month nutraceutical/diet protocol reverses hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia in a 60-year-old male with metabolic syndrome

A 60-year-old male with metabolic syndrome, hypercholesterolemia, hypertriglyceridemia, and hyperglycemia underwent a six-month personalized regimen of six nutraceuticals and a diet intervention. The protocol resulted in complete reversal of hypertriglyceridemia, hypercholesterolemia, and hyperlipidemia, along with significant weight loss and improved glycemic response.

Last updated: Aug 26, 2026•0 RCTs•📖 Read as article →

Evidence Score

Evidence Score32/100

Human RCT☆☆☆☆☆

Meta-analysis☆☆☆☆☆

Mechanism★★★★★

Safety★★★★☆

Confidencelow

Study Evidence

Study 1. Hyperlipidemia, Hypercholesterolemia, Hypertriglyceridemia, and Glycemic Response Improvement in a 60-year-Old Male with Metabolic Syndrome Through a Personalized Six-Month Nutraceutical/Diet Protocol: A Case Report.

observational

Brady DM, Coetzee O · Alternative therapies in health and medicine (2025)

Participants: N/A

Duration: 6 months

Intervention: Personalized six-month nutraceutical/diet protocol including Designs for Health Red Yeast Rice, Arterosil® HP, Metabolic Synergy™, Berberine-Evail™, GlucoSupreme™ Herbal, and Mito-NR™, plus dietary changes

Outcome: Reversal of hypertriglyceridemia, hypercholesterolemia, and hyperlipidemia; weight loss; improved glycemic response

Effect Size: N/A

Population: A single 60-year-old male with metabolic syndrome, sleep apnea, polyuria, hypercholesterolemia, hypertriglyceridemia, and hyperglycemia, with lifestyle factors including smoking, high sugar intake, poor diet, moderate alcohol, and lack of exercise

Result:

PubMed: 40662615

Mechanism Graph

Nutraceuticals (e.g., red yeast rice, berberine) and dietary changes reduce lipid synthesis and absorption

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Improved insulin sensitivity and glucose metabolism via berberine and other compounds

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Reduction in inflammatory and oxidative stress markers

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Result: Normalization of lipid profile and glycemic control

Limitations

⚠Single case report with no control group, limiting generalizability
⚠Confounding from multiple simultaneous interventions (nutraceuticals and diet) prevents attribution of effect to any single component
⚠No objective sleep apnea measures reported despite diagnosis

Frequently Asked Questions

What nutraceuticals were used in this protocol?▼

The protocol included Designs for Health Red Yeast Rice, Arterosil® HP, Metabolic Synergy™, Berberine-Evail™, GlucoSupreme™ Herbal, and Mito-NR™.

Did the patient have sleep apnea, and was it treated?▼

The patient was diagnosed with sleep apnea, but the abstract does not report any specific sleep apnea treatment or outcome; the focus was on metabolic improvements.

How long did the intervention last?▼

The intervention lasted six months.

What were the key metabolic outcomes?▼

Complete reversal of hypertriglyceridemia, hypercholesterolemia, and hyperlipidemia, significant weight loss, and positive changes in hyperglycemia.

Products

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References

1.Brady DM, Coetzee O. "Hyperlipidemia, Hypercholesterolemia, Hypertriglyceridemia, and Glycemic Response Improvement in a 60-year-Old Male with Metabolic Syndrome Through a Personalized Six-Month Nutraceutical/Diet Protocol: A Case Report.." Alternative therapies in health and medicine, 2025. PMID: 40662615

Disclaimer: This content is for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.