Amino AcidsL-Theanine

Chamomile and L-theanine beverage reduces menstrual pain and improves mood and sleep quality in young women with primary dysmenorrhea

A randomized, double-blind, placebo-controlled study found that daily consumption of a chamomile and L-theanine beverage (CTT) for five days around menstruation significantly reduced pain intensity by 57.17% (VAS) and 55.46% (NRS) compared to baseline. The intervention also significantly decreased severity of lower abdominal pain, back pain, depression, irritability, and daytime dysfunction by 31-56% in young women with primary dysmenorrhea.

Last updated: Aug 26, 2026•1 RCTs•📖 Read as article →

Evidence Score

Evidence Score44/100
Human RCT★★☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism★★★★★
Safety★★★★☆
Confidencelow

Study Evidence

Study 1. Effects of chamomile and -theanine beverage on menstrual pain, menstrual symptoms, mood, and sleep quality in young women experiencing primary dysmenorrhea: A randomized, double-blind, placebo-controlled study.

observational

Soh Z, Tan SC, Wong TH, Tan ST, Tan SS, Tan CX · Journal of food and drug analysis (2026)

Participants: N/A
Duration: 5 days per menstrual cycle (single cycle)
Intervention: Chamomile and L-theanine beverage (CTT) consumed daily for five consecutive days (starting two days before expected menstruation through first three days of menstruation)
Outcome: Menstrual pain intensity (VAS, NRS), menstrual symptoms (lower abdominal pain, back pain, loss of appetite, stomachache, body pain), mood (depression, irritability, complexation), and sleep quality (daytime dysfunction)
Effect Size: N/A (only percentage reductions reported)
Population: Young adult females with primary dysmenorrhea (n=30 total, 15 per group)

Result:

PubMed: 41525193DOI: 10.38212/2224-6614.3565

Mechanism Graph

Chamomile and L-theanine are consumed as a beverage
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Active compounds exert anti-inflammatory and anxiolytic effects
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Reduction in prostaglandin-mediated pain and stress response
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Result: Decreased menstrual pain, improved mood and sleep quality

Limitations

  • ⚠Small sample size (n=30 total, 15 per group)
  • ⚠Short intervention duration (only five days per menstrual cycle)

Frequently Asked Questions

How much did the chamomile and L-theanine beverage reduce menstrual pain?▼

The beverage reduced visual analog scale (VAS) pain scores by 57.17% and numerical rating scale (NRS) scores by 55.46% compared to baseline.

What menstrual symptoms improved with the chamomile and L-theanine drink?▼

Significant reductions were seen in lower abdominal pain (52.86%), back pain (56.29%), stomachache (43.14%), body pain (42.52%), loss of appetite (47.24%), depression (49.46%), and irritability (45.11%).

Did the placebo (chamomile-flavored beverage) have any effects?▼

Yes, the non-CTT (placebo) group showed significant reductions in complexation, neuroticism, and confusion, but not in pain or other menstrual symptoms.

How long did participants consume the beverage?▼

Participants consumed the beverage daily for five consecutive days, starting two days before expected menstruation and continuing through the first three days of menstruation.

Products

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References

  1. 1.Soh Z, Tan SC, Wong TH, Tan ST, Tan SS, Tan CX. "Effects of chamomile and -theanine beverage on menstrual pain, menstrual symptoms, mood, and sleep quality in young women experiencing primary dysmenorrhea: A randomized, double-blind, placebo-controlled study.." Journal of food and drug analysis, 2026. PMID: 41525193 DOI: 10.38212/2224-6614.3565
Disclaimer: This content is for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.