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Comprehensive nursing intervention improves psychological outcomes, sleep quality, pain, and coping in patients with comorbid depression and thoracolumbar compression fracture

A comprehensive nursing intervention including psychological counseling, environmental optimization, individualized pain management, health education, structured rehabilitation, and daily living support significantly reduced depression (SDS: 56.83 vs. 70.17, p<0.001, d=1.64), anxiety (SAS: 54.30 vs. 67.50, p<0.001, d=1.69), sleep disturbance (PSQI: 7.83 vs. 12.47, p<0.001, d=1.70), and pain (VAS: 3.17 vs. 4.93, p<0.001, d=1.50) compared to conventional nursing. Positive coping increased (21.53 vs. 16.07, d=1.35) and negative coping decreased (7.83 vs. 11.27, d=1.36).

Last updated: Jul 7, 2026•0 RCTs•📖 Read as article →

Evidence Score

Evidence Score48/100
Human RCT☆☆☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism★★★★★
Safety★★★★☆
Confidencelow

Study Evidence

Study 1. Comprehensive nursing intervention improves psychological outcomes, sleep quality, pain, and coping in patients with comorbid depression and thoracolumbar compression fracture.

observational

Qi M, Wang W, Zhang M, Zhang H · Frontiers in psychiatry (2026)

Participants: 60
Duration: At admission to discharge (duration not specified)
Intervention: Comprehensive nursing intervention (psychological counseling, environmental optimization, individualized pain management, health education, structured rehabilitation, daily living support) versus conventional nursing
Outcome: Depression (SDS), anxiety (SAS), sleep quality (PSQI), pain (VAS), coping styles (SCSQ), nursing satisfaction
Effect Size: d=1.70 for sleep quality (PSQI), d=1.69 for anxiety, d=1.64 for depression, d=1.50 for pain, d=1.35 for positive coping, d=1.36 for negative coping
Population: 60 patients with comorbid depression and thoracolumbar compression fracture at a tertiary center in China

Result: A comprehensive nursing intervention including psychological counseling, environmental optimization, individualized pain management, health education, structured rehabilitation, and daily living support significantly reduced depression (SDS: 56.83 vs. 70.17, p<0.001, d=1.64), anxiety (SAS: 54.30 vs. 67.50, p<0.001, d=1.69), sleep disturbance (PSQI: 7.83 vs. 12.47, p<0.001, d=1.70), and pain (VAS: 3.17 vs. 4.93, p<0.001, d=1.50) compared to conventional nursing. Positive coping increased (21.53 vs. 16.07, d=1.35) and negative coping decreased (7.83 vs. 11.27, d=1.36).

PubMed: 42389394DOI: 10.3389/fpsyt.2026.1820844

Mechanism Graph

Psychological counseling reduces emotional distress and maladaptive coping
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Environmental optimization and individualized pain management lower pain perception
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Health education and structured rehabilitation improve functional recovery and self-efficacy
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Result: Reduced depression, anxiety, pain, sleep disturbance, and improved coping

Limitations

  • ⚠Non-randomized quasi-experimental design with historical control limits causal inference
  • ⚠Small sample size (n=60) reduces generalizability and statistical power

Frequently Asked Questions

What specific components were included in the comprehensive nursing intervention?▼

The intervention included psychological counseling, environmental optimization, individualized pain management, health education, structured rehabilitation, and daily living support.

How large were the improvements in sleep quality?▼

Sleep quality improved significantly with a mean PSQI score of 7.83 in the intervention group versus 12.47 in the control group, with a large effect size of d=1.70.

Was the study randomized?▼

No, this was a quasi-experimental study with a non-concurrent historical control group, not a randomized controlled trial.

What population was studied?▼

The study included 60 patients with comorbid depression and thoracolumbar compression fracture at a tertiary hospital in China.

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References

  1. 1.Qi M, Wang W, Zhang M, Zhang H. "Comprehensive nursing intervention improves psychological outcomes, sleep quality, pain, and coping in patients with comorbid depression and thoracolumbar compression fracture.." Frontiers in psychiatry, 2026. PMID: 42389394 DOI: 10.3389/fpsyt.2026.1820844
Disclaimer: This content is for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.