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Comprehensive nursing intervention improves sleep quality, psychological outcomes, pain, and coping in patients with comorbid depression and thoracolumbar compression fracture

Q: What specific components were included in the comprehensive nursing intervention?

The intervention included psychological counseling, environmental optimization, individualized pain management, health education, structured rehabilitation, and daily living support.

Q: How large was the effect on sleep quality?

The effect size for sleep quality improvement was very large (Cohen's d = 1.70), with the intervention group scoring 7.83 on the PSQI versus 12.47 in the control group.

Q: Was the study randomized?

No, this was a quasi-experimental study using a non-concurrent historical control group, which limits the strength of the conclusions.

Q: What were the main limitations of this study?

Key limitations include the non-randomized design, small sample size (n=60), and single-center setting, which reduce generalizability and causal inference.

A quasi-experimental study of 60 patients with comorbid depression and thoracolumbar compression fracture found that comprehensive nursing intervention (including psychological counseling, environmental optimization, individualized pain management, health education, structured rehabilitation, and daily living support) significantly improved sleep quality (PSQI: 7.83 vs. 12.47, p<0.001, d=1.70), depression (SDS: 56.83 vs. 70.17, p<0.001, d=1.64), anxiety (SAS: 54.30 vs. 67.50, p<0.001, d=1.69), and pain (VAS: 3.17 vs. 4.93, p<0.001, d=1.50) compared to conventional nursing.

Last updated: Jul 7, 2026•0 RCTs•📖 Read as article →

Evidence Score

Evidence Score48/100

Human RCT☆☆☆☆☆

Meta-analysis☆☆☆☆☆

Mechanism★★★★★

Safety★★★★☆

Confidencelow

Study Evidence

Study 1. Comprehensive nursing intervention improves psychological outcomes, sleep quality, pain, and coping in patients with comorbid depression and thoracolumbar compression fracture.

observational

Qi M, Wang W, Zhang M, Zhang H · Frontiers in psychiatry (2026)

Participants: 60

Duration: At admission to discharge (duration not specified)

Intervention: Comprehensive nursing intervention (psychological counseling, environmental optimization, individualized pain management, health education, structured rehabilitation, daily living support) versus conventional nursing

Outcome: Depression (SDS), anxiety (SAS), sleep quality (PSQI), pain (VAS), coping styles (SCSQ), nursing satisfaction

Effect Size: d=1.70 for sleep quality (PSQI), d=1.69 for anxiety, d=1.64 for depression, d=1.50 for pain, d=1.35 for positive coping, d=1.36 for negative coping

Population: 60 patients with comorbid depression and thoracolumbar compression fracture at a tertiary center in China

Result: A comprehensive nursing intervention including psychological counseling, environmental optimization, individualized pain management, health education, structured rehabilitation, and daily living support significantly reduced depression (SDS: 56.83 vs. 70.17, p<0.001, d=1.64), anxiety (SAS: 54.30 vs. 67.50, p<0.001, d=1.69), sleep disturbance (PSQI: 7.83 vs. 12.47, p<0.001, d=1.70), and pain (VAS: 3.17 vs. 4.93, p<0.001, d=1.50) compared to conventional nursing. Positive coping increased (21.53 vs. 16.07, d=1.35) and negative coping decreased (7.83 vs. 11.27, d=1.36).

PubMed: 42389394 DOI: 10.3389/fpsyt.2026.1820844

Mechanism Graph

Psychological counseling reduces emotional distress and maladaptive coping

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Individualized pain management decreases pain intensity and related sleep disruption

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Environmental optimization and structured rehabilitation promote physical comfort and activity

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Result: Improved sleep quality, reduced depression and anxiety, better coping, and higher satisfaction

Limitations

⚠Non-randomized quasi-experimental design with historical control limits causal inference
⚠Small sample size (n=60) reduces generalizability and statistical power
⚠Single-center study in China may not be representative of other populations or settings

Frequently Asked Questions

What specific components were included in the comprehensive nursing intervention?▼

The intervention included psychological counseling, environmental optimization, individualized pain management, health education, structured rehabilitation, and daily living support.

How large was the effect on sleep quality?▼

The effect size for sleep quality improvement was very large (Cohen's d = 1.70), with the intervention group scoring 7.83 on the PSQI versus 12.47 in the control group.

Was the study randomized?▼

No, this was a quasi-experimental study using a non-concurrent historical control group, which limits the strength of the conclusions.

What were the main limitations of this study?▼

Key limitations include the non-randomized design, small sample size (n=60), and single-center setting, which reduce generalizability and causal inference.

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References

1.Qi M, Wang W, Zhang M, Zhang H. "Comprehensive nursing intervention improves psychological outcomes, sleep quality, pain, and coping in patients with comorbid depression and thoracolumbar compression fracture.." Frontiers in psychiatry, 2026. PMID: 42389394 DOI: 10.3389/fpsyt.2026.1820844

Disclaimer: This content is for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.