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Homeopathic interventions do not significantly improve insomnia compared to control conditions

A systematic review and meta-analysis of 9 studies (6 RCTs and 3 non-randomized) found a moderate but non-significant effect of homeopathy on sleep outcomes (SMD = 0.63, 95% CI [-0.13, 1.39], p = 0.1051) with substantial heterogeneity (I² = 88.26%) and publication bias. The certainty of evidence was low, and most studies had high or critical risk of bias, leading to the conclusion that current evidence is insufficient to support homeopathy for insomnia.

Last updated: Aug 8, 2026•0 RCTs•1 Meta-analyses•📖 Read as article →

Evidence Score

Evidence Score49/100
Human RCT☆☆☆☆☆
Meta-analysis★★★☆☆
Mechanism★★★★★
Safety★★★★☆
Confidencelow

Study Evidence

Study 1. Effectiveness of homeopathic interventions for insomnia and sleep disorders: A systematic review and meta-analysis.

observational

Paracha MA, Fazal F, Abdul Jalil Khan S, Rizvi SS, Ali Afridi R, Mathangasinghe Y · Complementary therapies in medicine (2026)

Participants: N/A
Duration: N/A
Intervention: Homeopathic interventions (various remedies) compared to placebo, no treatment, or active care
Outcome: Sleep quality measures (e.g., PSQI, ISI)
Effect Size: SMD (Hedges' g) = 0.63, 95% CI [-0.13, 1.39]
Population: Adults (≥18 years) with primary insomnia

Result:

PubMed: 42551574DOI: 10.1016/j.ctim.2026.103413

Mechanism Graph

Homeopathic remedies are administered based on individualization principles
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Proposed mechanisms include placebo effects and potential biological effects of ultra-dilute substances
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No significant difference from control was observed in meta-analysis
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Result: No evidence of effectiveness beyond placebo

Limitations

  • ⚠High or critical risk of bias in most included studies
  • ⚠Substantial unexplained heterogeneity (I² = 88.26%)
  • ⚠Publication bias detected (Egger's test p = 0.0465)
  • ⚠Low certainty of evidence per GRADE assessment

Frequently Asked Questions

What is the overall conclusion of this meta-analysis on homeopathy for insomnia?▼

The meta-analysis found no statistically significant difference between homeopathic interventions and control conditions for improving insomnia, based on low certainty evidence.

How many studies were included in this systematic review?▼

Nine studies were included: six randomized controlled trials and three non-randomized studies.

What was the effect size for homeopathy on sleep outcomes?▼

The pooled effect size was SMD = 0.63 (95% CI [-0.13, 1.39]), which is moderate but not statistically significant.

Why is the evidence considered insufficient?▼

The evidence is insufficient due to high risk of bias in the included studies, substantial heterogeneity, publication bias, and low certainty of evidence.

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References

  1. 1.Paracha MA, Fazal F, Abdul Jalil Khan S, Rizvi SS, Ali Afridi R, Mathangasinghe Y. "Effectiveness of homeopathic interventions for insomnia and sleep disorders: A systematic review and meta-analysis.." Complementary therapies in medicine, 2026. PMID: 42551574 DOI: 10.1016/j.ctim.2026.103413
Disclaimer: This content is for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.