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Individualised homoeopathy reduces weekly bedwetting episodes in children with nocturnal enuresis.

A double-blind RCT in children with nocturnal enuresis found that individualised homoeopathy significantly reduced weekly bedwetting episodes compared to placebo, with a median reduction of -2.4 nights per week (p < 0.04). The study included 451 participants across five studies, but this specific finding comes from one RCT.

Last updated: Aug 26, 2026•1 RCTs•📖 Read as article →

Evidence Score

Evidence Score44/100
Human RCT★★☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism★★★★★
Safety★★★★☆
Confidencelow

Study Evidence

Study 1. Effectiveness of Homoeopathic Treatments for Sleep Disorders in Children and Adolescents: A Systematic Review According to the Principles of Evidence-Based Medicine.

observational

Upreti K, Frass M · Children (Basel, Switzerland) (2026)

Participants: N/A
Duration: Not specified
Intervention: Individualised homoeopathic treatment
Outcome: Weekly bedwetting episodes
Effect Size: Median reduction of -2.4 nights per week
Population: Children and adolescents with nocturnal enuresis

Result:

PubMed: 41597053DOI: 10.3390/children13010045

Mechanism Graph

Homoeopathic remedy selected based on individual symptoms
↓
Administration of highly diluted substance
↓
Unknown mechanism of action
↓
Reported reduction in bedwetting frequency

Limitations

  • ⚠Limited number of studies (only one RCT for enuresis)
  • ⚠High risk of bias in some included studies (e.g., open-label trial)
  • ⚠Small sample size overall (451 participants across all studies)

Frequently Asked Questions

What is individualised homoeopathy?▼

Individualised homoeopathy involves selecting a remedy based on the patient's unique physical, emotional, and mental symptoms, rather than using a standard remedy for a condition.

How significant was the reduction in bedwetting?▼

The median reduction was -2.4 nights per week, which was statistically significant (p < 0.04) compared to placebo.

Were there any side effects?▼

No serious adverse effects were reported in any of the included studies.

Is this evidence strong enough to recommend homoeopathy for bedwetting?▼

No, the authors caution that the number and quality of studies are limited, and larger, high-quality trials are needed before recommendations can be made.

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References

  1. 1.Upreti K, Frass M. "Effectiveness of Homoeopathic Treatments for Sleep Disorders in Children and Adolescents: A Systematic Review According to the Principles of Evidence-Based Medicine.." Children (Basel, Switzerland), 2026. PMID: 41597053 DOI: 10.3390/children13010045
Disclaimer: This content is for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.