Supplements

Sleep disturbances prospectively predict suicidal ideation in adults

In a prospective cohort study of 652 adults, sleep disturbance (PSQI ≥ 6) was associated with a nearly 4-fold increased odds of future suicidal ideation (OR = 3.97). This association remained significant after adjusting for depressive symptoms (OR = 1.59). Bidirectional associations were also observed.

Last updated: Jul 29, 2026•0 RCTs•📖 Read as article →

Evidence Score

Evidence Score34/100
Human RCT☆☆☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism★★★★★
Safety★★★★☆
Confidencelow

Study Evidence

Study 1. Sleep Problems as Prospective Predictors of Suicidal Ideation.

observational

Shimura A, Iida M, Takada Y, Furui Y, Inoue Y · Archives of suicide research : official journal of the International Academy for Suicide Research (2026)

Participants: N/A
Duration: 3 months
Intervention: Sleep disturbance (PSQI global score and sleep latency) as a predictor
Outcome: Suicidal ideation measured by the Suicidal Ideation Scale (SIS) at 3-month follow-up
Effect Size: OR = 3.97 (univariate), OR = 1.59 (adjusted for depressive symptoms)
Population: Adults (mean age 49.7 years) from a web survey panel and local city government officers in 2022

Result:

PubMed: 42472476DOI: 10.1080/13811118.2026.2703972

Mechanism Graph

Sleep disturbance (e.g., prolonged sleep latency) is assessed via PSQI
↓
Sleep problems may impair emotional regulation and increase distress
↓
Chronic sleep disruption may exacerbate or trigger suicidal ideation
↓
Sleep disturbance prospectively predicts suicidal ideation

Limitations

  • ⚠Self-reported data may introduce recall bias
  • ⚠Sample limited to Japanese adults from a web panel and government officers, limiting generalizability

Frequently Asked Questions

What sleep problems were most predictive of suicidal ideation?▼

The PSQI global score and sleep latency (time to fall asleep) were significant prospective predictors.

Did the association hold after controlling for depression?▼

Yes, sleep disturbance remained a significant predictor of suicidal ideation even after adjusting for depressive symptoms (OR = 1.59).

How common were sleep disturbances in this study?▼

Sleep disturbance (PSQI ≥ 6) was observed in 32.8% of participants.

What was the study design and follow-up period?▼

This was a prospective cohort study with a 3-month follow-up using cross-lagged model analyses.

Products

Affiliate links coming soon. We only recommend products that match the doses and forms used in the cited research.

References

  1. 1.Shimura A, Iida M, Takada Y, Furui Y, Inoue Y. "Sleep Problems as Prospective Predictors of Suicidal Ideation.." Archives of suicide research : official journal of the International Academy for Suicide Research, 2026. PMID: 42472476 DOI: 10.1080/13811118.2026.2703972
Disclaimer: This content is for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.