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Sleep quality does not significantly affect cardiorespiratory fitness (VO2 max) in apparently healthy young adults

This cross-sectional study compared VO2 max between normal and poor sleep categories in young medical students. Mean VO2 max was 42.50 mL/kg/min for normal sleepers and 41.89 mL/kg/min for poor sleepers, with no significant difference (p=0.77). No correlation was found between PSQI score and VO2 max (r=0.029, p=0.591).

Last updated: Aug 26, 2026•0 RCTs•📖 Read as article →

Evidence Score

Evidence Score32/100
Human RCT☆☆☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism★★★★★
Safety★★★★☆
Confidencelow

Study Evidence

Study 1. Effect of Sleep on Cardiorespiratory Fitness of Apparently Healthy Young Adults.

observational

Kandel S, Mahotra NB, Shrestha L, Bajimaya MM, Aryal V · Journal of Nepal Health Research Council (2026)

Participants: N/A
Duration: Cross-sectional (March 2023 to September 2024)
Intervention: Sleep quality categorized by PSQI score (normal vs poor sleep)
Outcome: VO2 max measured via Queen's College step test
Effect Size: N/A
Population: Apparently healthy young adults (medical students, 45 males, 19 females)

Result:

PubMed: 42638259DOI: 10.33314/jnhrc.v24i01.4730

Mechanism Graph

Sleep quality assessed using PSQI score
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Participants categorized into normal (PSQI < 5) and poor (PSQI ≥ 5) sleep groups
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VO2 max measured after Queen's College step test
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No significant difference or correlation found between sleep quality and VO2 max

Limitations

  • ⚠Cross-sectional design limits causal inference
  • ⚠Small sample size (n=64) and single-center recruitment
  • ⚠VO2 max estimated from step test rather than direct measurement
  • ⚠Potential confounding factors (e.g., physical activity, BMI) not controlled

Frequently Asked Questions

What is the relationship between sleep quality and VO2 max in young adults?▼

This study found no significant relationship between sleep quality (measured by PSQI) and VO2 max in apparently healthy young adults.

What was the mean VO2 max for normal and poor sleepers?▼

Normal sleepers had a mean VO2 max of 42.50 mL/kg/min, while poor sleepers had 41.89 mL/kg/min, with no significant difference.

How was sleep quality measured in this study?▼

Sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI) score, with participants categorized into normal and poor sleep groups.

What is the sample size and population of this study?▼

The study included 64 participants (45 males, 19 females) who were apparently healthy young medical students.

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References

  1. 1.Kandel S, Mahotra NB, Shrestha L, Bajimaya MM, Aryal V. "Effect of Sleep on Cardiorespiratory Fitness of Apparently Healthy Young Adults.." Journal of Nepal Health Research Council, 2026. PMID: 42638259 DOI: 10.33314/jnhrc.v24i01.4730
Disclaimer: This content is for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.