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The prevalence of common mental disorders, anxiety, depression, burnout, insomnia, and stress among primary healthcare workers in Brazil is fragmented and requires systematic review and meta-analysis to consolidate estimates.

This protocol describes a systematic review and prevalence meta-analysis to consolidate prevalence estimates of mental health outcomes among primary healthcare workers in Brazil. The review will search multiple databases from inception to 16 September 2025, include quantitative observational studies, and pool prevalence using random-effects models. The study aims to synthesize associated sociodemographic, occupational, and organizational factors.

Last updated: Aug 21, 2026•0 RCTs•1 Meta-analyses•📖 Read as article →

Evidence Score

Evidence Score47/100
Human RCT☆☆☆☆☆
Meta-analysis★★★☆☆
Mechanism★★★★★
Safety★★★★☆
Confidencelow

Study Evidence

Study 1. Prevalence and factors associated with symptoms of common mental disorders, anxiety, depression, burnout, insomnia and stress among primary healthcare workers in Brazil: protocol for a systematic review and prevalence meta-analysis.

observational

Antonucci BL, Pereira GR, Rocha K, Lima TM, Araújo DC · BMJ open (2026)

Participants: N/A
Duration: Not applicable
Intervention: Not applicable (systematic review protocol)
Outcome: Prevalence of common mental disorders, anxiety, depression, burnout, insomnia, and stress
Effect Size: N/A
Population: Primary healthcare workers in Brazil within the Unified Health System (SUS), including health professionals and other occupational groups

Result:

PubMed: 42613114DOI: 10.1136/bmjopen-2026-118825

Mechanism Graph

Search multiple databases and grey literature for relevant studies
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Screen records and full texts independently by two reviewers
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Assess risk of bias using Joanna Briggs Institute checklist
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Pool prevalence estimates using random-effects models and quantify heterogeneity
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Synthesize associated factors narratively

Limitations

  • ⚠The abstract does not report actual prevalence data, only the protocol for the review
  • ⚠Potential heterogeneity in instruments and cut-offs across studies may limit comparability
  • ⚠Meta-analysis of associations may not be feasible due to variability in exposure definitions

Frequently Asked Questions

What is the purpose of this systematic review?▼

To consolidate prevalence estimates and synthesize associated factors of mental health outcomes among primary healthcare workers in Brazil.

Which databases will be searched?▼

MEDLINE (via PubMed), Embase, PsycINFO, CINAHL, and BVS/LILACS, plus grey literature from Google Scholar and CAPES Theses and Dissertations.

What types of studies will be included?▼

Quantitative observational studies conducted in Brazil with workers linked to primary healthcare within the SUS, using validated instruments and explicit case definitions.

How will prevalence estimates be pooled?▼

Using random-effects models, primarily binomial models, with heterogeneity quantified by I², τ², and Q, and prediction intervals estimated.

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References

  1. 1.Antonucci BL, Pereira GR, Rocha K, Lima TM, Araújo DC. "Prevalence and factors associated with symptoms of common mental disorders, anxiety, depression, burnout, insomnia and stress among primary healthcare workers in Brazil: protocol for a systematic review and prevalence meta-analysis.." BMJ open, 2026. PMID: 42613114 DOI: 10.1136/bmjopen-2026-118825
Disclaimer: This content is for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.