A multispecies probiotic intervention improves sleep quality in individuals with self-reported sleep disturbances
In a randomized, double-blind, placebo-controlled trial, 94 participants with poor sleep quality (PSQI > 5) received either a multispecies probiotic (OMNiBiOTiC® STRESS Repair) or placebo for 28 days. The probiotic group showed a significantly greater improvement in sleep quality (PSQI score 6.8 ± 2.9 vs. 7.7 ± 3.1; p = 0.036) compared to placebo, driven by improvements in sleep efficiency and latency.
This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.
A multispecies probiotic intervention improves sleep quality in individuals with self-reported sleep disturbances The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 44/100 (low).
The Claim
A multispecies probiotic intervention improves sleep quality in individuals with self-reported sleep disturbances
This conclusion is most relevant to: 130 volunteers with self-reported impaired sleep quality (PSQI > 5); 94 completers (88% female, mean age ~41 years).
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸The beneficial effect of a multispecies probiotic intervention on quality of sleep - a randomized, double-blinded, placebo-controlled study. (Journal of psychiatric research, 2026) —
How It Works
The proposed biological pathway:
- ▸Probiotic bacteria are ingested and partially recovered in the gut microbiome
- ▸Microbiome composition shifts (beta diversity change)
- ▸Gut-brain axis modulation influences circadian rhythms
- ▸Improved sleep efficiency and latency, leading to better overall sleep quality
Who Might Benefit
Evidence fit by population:
- ▸130 volunteers with self-reported impaired sleep quality (PSQI > 5); 94 completers (88% female, mean age ~41 years)
Recommended Dose
N/A (specific dose not reported in abstract)
Limitations & Caveats
Important context when interpreting this evidence:
- ▸High dropout rate (36 of 130 participants did not complete the study)
- ▸Predominantly female sample (88%), limiting generalizability to males
- ▸No significant effect on quality of life or perceived stress, suggesting specific rather than broad benefits
Frequently Asked Questions
What probiotic was used in this study?▼
The study used a multispecies probiotic called OMNiBiOTiC® STRESS Repair.
How long did the probiotic intervention last?▼
The intervention lasted 28 days.
Did the probiotic improve stress or quality of life?▼
No, the intervention did not significantly influence quality of life or perceived stress.
What was the main sleep improvement observed?▼
The probiotic improved sleep efficiency and latency, leading to a lower PSQI score (better sleep quality) compared to placebo.
References
- 1.Horvath A, Haller R, Schmid-Zalaudek K, Goswami N, Wagner-Skacel J, Habisch H, Madl T, Stadlbauer V. “The beneficial effect of a multispecies probiotic intervention on quality of sleep - a randomized, double-blinded, placebo-controlled study..” Journal of psychiatric research, 2026. PMID: 41637999 DOI: 10.1016/j.jpsychires.2026.01.040