Company cafeteria use, regular exercise, and breakfast consumption are associated with reduced hyperuricemia risk, while smoking and breakfast skipping increase risk among male manufacturing workers
In a cross-sectional study of 613 male manufacturing workers in Japan, 20.6% had high uric acid (≥7.0 mg/dL). Multivariable logistic regression identified smoking (OR=1.861), skipping breakfast ≥3 times/week (OR=1.684), and higher ALT (OR=1.035) as risk factors, while company cafeteria use (OR=0.528), regular exercise (OR=0.501), older age (OR=0.952), and higher eGFR (OR=0.969) were protective.
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Company cafeteria use, regular exercise, and breakfast consumption are associated with reduced hyperuricemia risk, while smoking and breakfast skipping increase risk among male manufacturing workers The current body of evidence comprises 1 study. EvidenceHub rates the overall confidence at 34/100 (low).
The Claim
Company cafeteria use, regular exercise, and breakfast consumption are associated with reduced hyperuricemia risk, while smoking and breakfast skipping increase risk among male manufacturing workers
This conclusion is most relevant to: 613 male workers at a single manufacturing company in Japan (≥1,000 employees, no night shifts), mean age 39.9 years.
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Workplace Environment and Lifestyle Factors Associated With Hyperuricemia Risk Among Male Manufacturing Workers: A Cross-Sectional Study at a Single Company in Japan. (Cureus, 2026) —
How It Works
The proposed biological pathway:
- ▸Smoking may increase oxidative stress and purine metabolism
- ▸Breakfast skipping may alter metabolic regulation and insulin sensitivity
- ▸Company cafeteria use may provide healthier meal options
- ▸Regular exercise improves metabolic health and uric acid excretion
Who Might Benefit
Evidence fit by population:
- ▸613 male workers at a single manufacturing company in Japan (≥1,000 employees, no night shifts), mean age 39.9 years
Recommended Dose
N/A
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Cross-sectional design prevents causal inference
- ▸Single company and male-only sample limits generalizability
- ▸Self-reported questionnaire data may introduce recall bias
- ▸No night shift workers included, limiting applicability to shift workers
Frequently Asked Questions
What is the main finding of this study?▼
Company cafeteria use, regular exercise, and not skipping breakfast were associated with lower hyperuricemia risk, while smoking and frequent breakfast skipping increased risk among male manufacturing workers.
How many participants had high uric acid?▼
126 out of 613 participants (20.6%) had serum uric acid levels ≥7.0 mg/dL.
What lifestyle factors were examined?▼
Breakfast skipping, exercise habits, smoking, alcohol consumption, and sleep duration were assessed via questionnaire.
What workplace factors were studied?▼
Job type, lunch type (company cafeteria vs. other), and fluid intake were evaluated as workplace environment factors.
References
- 1.Takahashi Y, Tanojiri R, Kumakura R, Okamoto R, Yu S, Omote S. “Workplace Environment and Lifestyle Factors Associated With Hyperuricemia Risk Among Male Manufacturing Workers: A Cross-Sectional Study at a Single Company in Japan..” Cureus, 2026. PMID: 42524050 DOI: 10.7759/cureus.111627