Endovenous ablation with concomitant phlebectomy improves sleep quality in patients with chronic venous disease
In a prospective observational study of 77 patients with lower extremity CVD, endovenous ablation (frequently combined with phlebectomy) was associated with significant improvement in sleep quality at 1-month follow-up. The median PSQI score decreased from 6 to 5 (P < .001), and the proportion of patients with poor sleep quality (PSQI > 5) declined from 66.2% to 41.6%.
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Endovenous ablation with concomitant phlebectomy improves sleep quality in patients with chronic venous disease The current body of evidence comprises 1 study. EvidenceHub rates the overall confidence at 32/100 (low).
The Claim
Endovenous ablation with concomitant phlebectomy improves sleep quality in patients with chronic venous disease
This conclusion is most relevant to: 77 patients with lower extremity chronic venous disease (CVD) undergoing endovenous ablation in Vietnam.
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Sleep quality after endovenous ablation with concomitant phlebectomy in patients with chronic venous disease: A prospective observational study in Vietnam. (Journal of vascular surgery cases and innovative techniques, 2026) — In a prospective observational study of 77 patients with lower extremity CVD, endovenous ablation (frequently combined with phlebectomy) was associated with significant improvement in sleep quality at 1-month follow-up. The median PSQI score decreased from 6 to 5 (P < .001), and the proportion of patients with poor sleep quality (PSQI > 5) declined from 66.2% to 41.6%.
How It Works
The proposed biological pathway:
- ▸CVD causes venous hypertension leading to leg pain, heaviness, edema, and nocturnal cramps
- ▸These symptoms worsen at night and impair sleep quality
- ▸Endovenous ablation relieves venous symptoms
- ▸Reduction in symptom burden leads to improved sleep quality
Who Might Benefit
Evidence fit by population:
- ▸77 patients with lower extremity chronic venous disease (CVD) undergoing endovenous ablation in Vietnam
Recommended Dose
N/A
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Observational design with no control group
- ▸Short follow-up period (1 month) limiting assessment of durability
- ▸Lack of objective sleep measures (e.g., actigraphy or polysomnography)
Frequently Asked Questions
What is the PSQI score threshold for poor sleep quality?▼
A PSQI score greater than 5 indicates poor sleep quality.
Which components of sleep quality improved after the procedure?▼
Significant improvements were observed in subjective sleep quality, sleep latency, sleep duration, sleep disturbances, and daytime dysfunction, but not in habitual sleep efficiency or use of sleep medication.
How many patients were included in this study?▼
The study included 77 patients with lower extremity chronic venous disease.
What were the main symptoms of CVD that might affect sleep?▼
Symptoms included leg pain, heaviness, edema, and nocturnal cramps, which often worsen at night.
References
- 1.Huyen Trang HN, Vy HT, Cam Van NN, Hong Anh VT, Kieu Nga PT, Hoa HN, Kim Thao VT, Thanh Truc NT, Bang HT. “Sleep quality after endovenous ablation with concomitant phlebectomy in patients with chronic venous disease: A prospective observational study in Vietnam..” Journal of vascular surgery cases and innovative techniques, 2026. PMID: 42494507 DOI: 10.1016/j.jvscit.2026.102358