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Endovenous ablation with concomitant phlebectomy improves sleep quality in patients with chronic venous disease

In a prospective observational study of 77 patients with lower extremity CVD, endovenous ablation (frequently combined with phlebectomy) was associated with significant improvement in sleep quality at 1-month follow-up. The median PSQI score decreased from 6 to 5 (P < .001), and the proportion of patients with poor sleep quality (PSQI > 5) declined from 66.2% to 41.6%.

Last updated: Aug 2, 2026•0 RCTs•📖 Read as article →

Evidence Score

Evidence Score32/100
Human RCT☆☆☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism★★★★★
Safety★★★★☆
Confidencelow

Study Evidence

Study 1. Sleep quality after endovenous ablation with concomitant phlebectomy in patients with chronic venous disease: A prospective observational study in Vietnam.

observational

Huyen Trang HN, Vy HT, Cam Van NN, Hong Anh VT, Kieu Nga PT, Hoa HN, Kim Thao VT, Thanh Truc NT, Bang HT · Journal of vascular surgery cases and innovative techniques (2026)

Participants: 77
Duration: 1 month
Intervention: Endovenous ablation (frequently combined with phlebectomy)
Outcome: Sleep quality measured by Pittsburgh Sleep Quality Index (PSQI) global and component scores
Effect Size: N/A
Population: 77 patients with lower extremity chronic venous disease (CVD) undergoing endovenous ablation in Vietnam

Result: In a prospective observational study of 77 patients with lower extremity CVD, endovenous ablation (frequently combined with phlebectomy) was associated with significant improvement in sleep quality at 1-month follow-up. The median PSQI score decreased from 6 to 5 (P < .001), and the proportion of patients with poor sleep quality (PSQI > 5) declined from 66.2% to 41.6%.

PubMed: 42494507DOI: 10.1016/j.jvscit.2026.102358

Mechanism Graph

CVD causes venous hypertension leading to leg pain, heaviness, edema, and nocturnal cramps
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These symptoms worsen at night and impair sleep quality
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Endovenous ablation relieves venous symptoms
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Reduction in symptom burden leads to improved sleep quality

Limitations

  • ⚠Observational design with no control group
  • ⚠Short follow-up period (1 month) limiting assessment of durability
  • ⚠Lack of objective sleep measures (e.g., actigraphy or polysomnography)

Frequently Asked Questions

What is the PSQI score threshold for poor sleep quality?▼

A PSQI score greater than 5 indicates poor sleep quality.

Which components of sleep quality improved after the procedure?▼

Significant improvements were observed in subjective sleep quality, sleep latency, sleep duration, sleep disturbances, and daytime dysfunction, but not in habitual sleep efficiency or use of sleep medication.

How many patients were included in this study?▼

The study included 77 patients with lower extremity chronic venous disease.

What were the main symptoms of CVD that might affect sleep?▼

Symptoms included leg pain, heaviness, edema, and nocturnal cramps, which often worsen at night.

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References

  1. 1.Huyen Trang HN, Vy HT, Cam Van NN, Hong Anh VT, Kieu Nga PT, Hoa HN, Kim Thao VT, Thanh Truc NT, Bang HT. "Sleep quality after endovenous ablation with concomitant phlebectomy in patients with chronic venous disease: A prospective observational study in Vietnam.." Journal of vascular surgery cases and innovative techniques, 2026. PMID: 42494507 DOI: 10.1016/j.jvscit.2026.102358
Disclaimer: This content is for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.