GBP (Ginkgo biloba extract with phosphatidylserine) improves delayed verbal memory and reaction time in healthy adults and those with moderate stress.
Two exploratory RCTs found that 480 mg/day of GBP for 4 weeks improved delayed verbal memory and reaction time versus placebo in healthy volunteers. A second study in adults with moderate stress showed mood benefits and a trend toward faster reaction times at both 240 mg and 480 mg doses.
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GBP (Ginkgo biloba extract with phosphatidylserine) improves delayed verbal memory and reaction time in healthy adults and those with moderate stress. The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 42/100 (low).
The Claim
GBP (Ginkgo biloba extract with phosphatidylserine) improves delayed verbal memory and reaction time in healthy adults and those with moderate stress.
This conclusion is most relevant to: Healthy volunteers (first trial) and adults experiencing moderate stress (second trial)..
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Health Benefits of a Standardized Ginkgo biloba Extract Associated With Phosphatidylserine in Alleviating Mental Stress and Cognitive Performance: Results From Two Exploratory Randomized Trials. (Food science & nutrition, 2026) —
How It Works
The proposed biological pathway:
- ▸GBP combines antioxidant, neuroprotective, and nootropic properties of Ginkgo biloba and phosphatidylserine
- ▸Phosphatidylserine modulates neurotransmitter activity
- ▸Ginkgo biloba improves mental functions through enhanced blood flow and neuroprotection
- ▸Result: Improved cognitive performance and mood regulation
Who Might Benefit
Evidence fit by population:
- ▸Healthy volunteers (first trial) and adults experiencing moderate stress (second trial).
Recommended Dose
480 mg/day
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Results from the second study were more modest than expected based on the first study
- ▸Exploratory nature of the trials requires further research to consolidate preliminary evidence
Frequently Asked Questions
What is GBP?▼
GBP is a standardized combination of Ginkgo biloba extract and phosphatidylserine, tested for cognitive and mood benefits.
What dose of GBP was effective?▼
The primary effective dose was 480 mg/day, though 240 mg/day also showed trends in reaction time improvements.
How long did the study last?▼
Both trials lasted 4 weeks, with acute effects measured at 60 and 180 minutes after a single dose.
Who might benefit from GBP?▼
Healthy adults and those experiencing moderate stress may see improvements in memory, reaction time, and mood.
References
- 1.Hawkins K, Davis J, Matias CA, Wilson G, Lowery R, Misiano P, Petrangolini G, Wilson J. “Health Benefits of a Standardized Ginkgo biloba Extract Associated With Phosphatidylserine in Alleviating Mental Stress and Cognitive Performance: Results From Two Exploratory Randomized Trials..” Food science & nutrition, 2026. PMID: 42294065 DOI: 10.1002/fsn3.72001