GBP supplementation improves delayed verbal memory and reaction time in healthy adults and those with moderate stress
Two exploratory RCTs found that 480 mg/day of a standardized Ginkgo biloba extract with phosphatidylserine (GBP) for 4 weeks improved delayed verbal memory and reaction time versus placebo in healthy volunteers. A second trial in adults with moderate stress showed mood benefits and a trend toward faster reaction times at both 240 mg and 480 mg doses. Effects on cognitive models in the second study were more modest than expected.
This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.
GBP supplementation improves delayed verbal memory and reaction time in healthy adults and those with moderate stress The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 42/100 (low).
The Claim
GBP supplementation improves delayed verbal memory and reaction time in healthy adults and those with moderate stress
This conclusion is most relevant to: Healthy volunteers (trial 1) and adults experiencing moderate stress (trial 2).
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Health Benefits of a Standardized Ginkgo biloba Extract Associated With Phosphatidylserine in Alleviating Mental Stress and Cognitive Performance: Results From Two Exploratory Randomized Trials. (Food science & nutrition, 2026) —
How It Works
The proposed biological pathway:
- ▸Ginkgo biloba provides antioxidant and neuroprotective effects
- ▸Phosphatidylserine modulates neurotransmitter activity
- ▸Combined ingredients enhance nootropic properties
- ▸Result: Improved cognitive function and mood regulation
Who Might Benefit
Evidence fit by population:
- ▸Healthy volunteers (trial 1) and adults experiencing moderate stress (trial 2)
Recommended Dose
480 mg/day
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Exploratory design with modest cognitive effects in the second study
- ▸Preliminary evidence requiring further research to consolidate findings
Frequently Asked Questions
What is GBP?▼
GBP is a combination of standardized Ginkgo biloba extract and phosphatidylserine, tested for mental health benefits.
How long was the supplementation period?▼
Both trials used a 4-week supplementation period with additional acute single-dose testing.
Who were the participants?▼
Healthy volunteers in the first trial and adults with moderate stress in the second trial.
What cognitive improvements were observed?▼
Improvements in delayed verbal memory and reaction time, with a trend toward faster processing speed.
References
- 1.Hawkins K, Davis J, Matias CA, Wilson G, Lowery R, Misiano P, Petrangolini G, Wilson J. “Health Benefits of a Standardized Ginkgo biloba Extract Associated With Phosphatidylserine in Alleviating Mental Stress and Cognitive Performance: Results From Two Exploratory Randomized Trials..” Food science & nutrition, 2026. PMID: 42294065 DOI: 10.1002/fsn3.72001