Longer sleep onset latency is significantly correlated with lower time in range in adults with cystic fibrosis-related diabetes
In a remote pilot study of 30 adults with CFRD, longer sleep onset latency measured by actigraphy was significantly correlated with lower time in range (TIR), indicating worse glycemic control. The study found that 76.7% of participants reported poor sleep quality, with 46.7% endorsing clinically significant insomnia symptoms.
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Longer sleep onset latency is significantly correlated with lower time in range in adults with cystic fibrosis-related diabetes The current body of evidence comprises 1 study. EvidenceHub rates the overall confidence at 34/100 (low).
The Claim
Longer sleep onset latency is significantly correlated with lower time in range in adults with cystic fibrosis-related diabetes
This conclusion is most relevant to: Adults with cystic fibrosis-related diabetes (mean age 43.7 years, 83.3% female, 93.3% White).
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Sleep patterns and glycemia in adults with cystic fibrosis-related diabetes: a remote pilot study. (Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2026) —
How It Works
The proposed biological pathway:
- ▸Sleep disturbance is prevalent in cystic fibrosis
- ▸Sleep disturbance may contribute to dysglycemia in CFRD
- ▸Longer sleep onset latency was measured via actigraphy
- ▸Longer sleep onset latency correlated with lower time in range
Who Might Benefit
Evidence fit by population:
- ▸Adults with cystic fibrosis-related diabetes (mean age 43.7 years, 83.3% female, 93.3% White)
Recommended Dose
N/A
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Small sample size (n=30) limits generalizability
- ▸Observational design cannot establish causality
- ▸High proportion of female and White participants may limit applicability to other demographics
Frequently Asked Questions
What is the main finding of this study?▼
The study found that longer sleep onset latency is significantly correlated with lower time in range (a measure of glycemic control) in adults with cystic fibrosis-related diabetes.
How was sleep measured in this study?▼
Sleep was measured using wrist actigraphy, which provided estimates of sleep duration, efficiency, and onset latency, along with validated surveys for sleep quality and disorders.
What percentage of participants had poor sleep quality?▼
76.7% of participants reported poor overall sleep quality, and 46.7% had clinically significant insomnia symptoms.
Is this study applicable to all people with cystic fibrosis?▼
The study focused on adults with CFRD, and the sample was predominantly female and White, so results may not generalize to other populations or those without diabetes.
References
- 1.Sharma A, Vassilakis E, Deng H, Salwen-Deremer JK, Bartley BL, Putman MS, Dashti HS. “Sleep patterns and glycemia in adults with cystic fibrosis-related diabetes: a remote pilot study..” Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2026. PMID: 42457443 DOI: 10.1016/j.jcf.2026.07.005