MobACT, a guided internet-based Acceptance and Commitment Therapy programme, may improve pain acceptance in Italian adults with chronic pain.
This study protocol describes a two-arm randomized controlled trial evaluating the effectiveness and cost-effectiveness of MobACT, a guided internet-based ACT intervention, for Italian adults with medically verified chronic pain. The primary outcome is pain acceptance measured by the Chronic Pain Acceptance Questionnaire at post-intervention (T1), with secondary outcomes including pain intensity, pain interference, sleep quality, and psychological flexibility. The trial compares immediate MobACT to a waitlist control, with a 6-month follow-up in the intervention group only.
This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.
MobACT, a guided internet-based Acceptance and Commitment Therapy programme, may improve pain acceptance in Italian adults with chronic pain. The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 42/100 (low).
The Claim
MobACT, a guided internet-based Acceptance and Commitment Therapy programme, may improve pain acceptance in Italian adults with chronic pain.
This conclusion is most relevant to: Italian adults with medically verified chronic pain.
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Effectiveness and cost-effectiveness of a guided internet-based Acceptance and Commitment Therapy intervention (MobACT) for adults with Chronic Pain in Italy: study protocol for a randomized controlled trial. (Frontiers in psychology, 2026) —
How It Works
The proposed biological pathway:
- ▸Participants receive guided internet-based ACT sessions
- ▸Participants engage in acceptance and mindfulness exercises
- ▸Participants develop psychological flexibility and reduce experiential avoidance
- ▸Result: Improved pain acceptance and reduced pain interference
Who Might Benefit
Evidence fit by population:
- ▸Italian adults with medically verified chronic pain
Recommended Dose
N/A
Limitations & Caveats
Important context when interpreting this evidence:
- ▸The waitlist control design may overestimate treatment effects due to expectancy bias
- ▸Only the intervention group has a 6-month follow-up, limiting long-term comparison
- ▸The study is a protocol; results are not yet available
Frequently Asked Questions
What is MobACT?▼
MobACT is a guided internet-based Acceptance and Commitment Therapy programme designed for Italian adults with chronic pain.
What is the primary outcome of this trial?▼
The primary outcome is pain acceptance, measured by the Chronic Pain Acceptance Questionnaire at post-intervention.
Who can participate in this study?▼
Italian adults with medically verified chronic pain are eligible for this randomized controlled trial.
How long is the follow-up period?▼
The intervention group has a 6-month follow-up (T2), while the waitlist control group receives MobACT only after the primary assessment (T1).
References
- 1.Semonella M, De Luca A, Rodighiero C, Andersson G, Buhrman M, Donisi V, Guerrini Usubini A, Landi G, Manna C, Pasini I, Perlini C, Pietrabissa G, Segattini B, Tossani E, Grandi S, Del Piccolo L, Castelnuovo G. “Effectiveness and cost-effectiveness of a guided internet-based Acceptance and Commitment Therapy intervention (MobACT) for adults with Chronic Pain in Italy: study protocol for a randomized controlled trial..” Frontiers in psychology, 2026. PMID: 42516192 DOI: 10.3389/fpsyg.2026.1813251