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MOTIVATE increases device-measured moderate-to-vigorous physical activity (MVPA) at 3 and 6 months among community-dwelling stroke survivors compared with general PA information.

The MOTIVATE trial is a hybrid type 1 effectiveness-implementation randomized controlled trial testing a theory-informed, co-designed behavior change intervention to increase physical activity after stroke. The primary outcome is average daily minutes of moderate-to-vigorous physical activity (MVPA) measured by Fitbit Inspire 3 at 3 and 6 months. The trial aims to recruit 120 participants to detect a 10-minute/day difference in MVPA with 80% power, allowing for 20% attrition.

1 min readUpdated Aug 26, 20261 RCTsView structured evidence →
Evidence Score44/100
Human RCT★★☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism★★★★★
Safety★★★★
Confidencelow

This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.

MOTIVATE increases device-measured moderate-to-vigorous physical activity (MVPA) at 3 and 6 months among community-dwelling stroke survivors compared with general PA information. The current body of evidence comprises 1 study, including 1 randomized controlled trial. EvidenceHub rates the overall confidence at 44/100 (low).

The Claim

MOTIVATE increases device-measured moderate-to-vigorous physical activity (MVPA) at 3 and 6 months among community-dwelling stroke survivors compared with general PA information.

This conclusion is most relevant to: Community-dwelling stroke survivors aged ≥21 years, ≥6 months post-stroke, ambulant with or without an aid..

What the Research Shows

The conclusion draws on 1 linked study. Highlights from the cited literature:

  • Multi-mOdal training program to promote physical actIVity after sTrokE (MOTIVATE): Protocol for effectiveness and economic outcomes in a hybrid type 1 effectiveness-implementation randomised controlled trial. (Contemporary clinical trials, 2026) —

How It Works

The proposed biological pathway:

  • MOTIVATE intervention delivered to stroke survivors
  • Behavior change techniques target self-efficacy, fatigue, mood, and sleep
  • Increased motivation and capability to engage in physical activity
  • Increased daily MVPA at 3 and 6 months

Who Might Benefit

Evidence fit by population:

  • Community-dwelling stroke survivors aged ≥21 years, ≥6 months post-stroke, ambulant with or without an aid.

Limitations & Caveats

Important context when interpreting this evidence:

  • Protocol paper; results not yet available, so effectiveness is not confirmed.
  • Primary outcome relies on Fitbit device, which may have measurement error or adherence issues.
  • Sample size calculation assumes 20% attrition, which may affect power if attrition is higher.

Frequently Asked Questions

What is the MOTIVATE intervention?

MOTIVATE is a theory-informed, co-designed behavior change intervention to promote physical activity after stroke, delivered to community-dwelling stroke survivors.

How is physical activity measured in the MOTIVATE trial?

Physical activity is measured using a Fitbit Inspire 3 device, which records daily minutes of moderate-to-vigorous physical activity (MVPA).

Who is eligible for the MOTIVATE trial?

Adults aged 21 years or older, at least 6 months post-stroke, living at home, and able to walk with or without an aid.

What is the primary outcome of the MOTIVATE trial?

The primary outcome is the average daily minutes of moderate-to-vigorous physical activity (MVPA) at 3 and 6 months post-randomization.

References

  1. 1.Thilarajah S, Hao PY, De Silva DA, Thumboo J, Leng LL, Hollis J, Bird ML, Clark RA, Wang J, Kaur P, Khim KL. “Multi-mOdal training program to promote physical actIVity after sTrokE (MOTIVATE): Protocol for effectiveness and economic outcomes in a hybrid type 1 effectiveness-implementation randomised controlled trial..” Contemporary clinical trials, 2026. PMID: 42632450 DOI: 10.1016/j.cct.2026.108441
Disclaimer: This article is auto-generated from structured research data for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.