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Patients with late-life depression exhibit subjective-device-estimated discrepancies in sleep parameters, with greater depressive symptom severity associated with greater underestimation of total sleep time

In a cross-sectional study of 94 patients with late-life depression, subjective reports significantly differed from device-estimated measures for total sleep time (TST), sleep onset latency (SOL), and sleep efficiency (SE). Greater depressive symptom severity was associated with greater subjective underestimation of TST (p = 0.037), while later age at first onset was associated with greater subjective underestimation of SE (p = 0.013).

1 min readUpdated Jul 14, 20260 RCTsView structured evidence →
Evidence Score32/100
Human RCT☆☆☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism★★★★★
Safety★★★★
Confidencelow

This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.

Patients with late-life depression exhibit subjective-device-estimated discrepancies in sleep parameters, with greater depressive symptom severity associated with greater underestimation of total sleep time The current body of evidence comprises 1 study. EvidenceHub rates the overall confidence at 32/100 (low).

The Claim

Patients with late-life depression exhibit subjective-device-estimated discrepancies in sleep parameters, with greater depressive symptom severity associated with greater underestimation of total sleep time

This conclusion is most relevant to: 94 patients with late-life depression.

What the Research Shows

The conclusion draws on 1 linked study. Highlights from the cited literature:

  • Subjective-Device-Estimated Sleep Discrepancies in Late-Life Depression: Agreement and Associated Factors. (Alpha psychiatry, 2026) —

How It Works

The proposed biological pathway:

  • Subjective sleep reports are collected via self-designed form for previous night's TST, SOL, and SE
  • Device-estimated sleep parameters are obtained via portable sleep respiratory monitoring
  • Bland-Altman analysis and Wilcoxon signed-rank tests compare subjective and device-estimated measures
  • Result: Significant discrepancies found, with subjective underestimation of TST and SE and overestimation of SOL

Who Might Benefit

Evidence fit by population:

  • 94 patients with late-life depression

Limitations & Caveats

Important context when interpreting this evidence:

  • Cross-sectional design limits causal inference
  • Use of a self-designed form for subjective sleep assessment may not be validated against standardized questionnaires

Frequently Asked Questions

What sleep parameters showed discrepancies in late-life depression?

Total sleep time (TST), sleep onset latency (SOL), and sleep efficiency (SE) all showed significant subjective-device-estimated discrepancies.

Which factor was associated with underestimation of total sleep time?

Greater depressive symptom severity was associated with greater subjective underestimation of total sleep time (p = 0.037).

Was there any association with age at first onset of depression?

Later age at first onset was associated with greater subjective underestimation of sleep efficiency (p = 0.013), and showed a trend toward overestimation of sleep onset latency (p = 0.047, but not significant after adjusting for sex).

What is the clinical implication of this study?

Combining device-estimated sleep monitoring with subjective sleep assessment is recommended for a more comprehensive understanding of sleep status in late-life depression.

References

  1. 1.Wang Q, Gong Y, Ji J, Zhang Y, Lu M, Song M, Zhang X, Zhao Y, Miao Q. “Subjective-Device-Estimated Sleep Discrepancies in Late-Life Depression: Agreement and Associated Factors..” Alpha psychiatry, 2026. PMID: 42416181 DOI: 10.31083/AP50350
Disclaimer: This article is auto-generated from structured research data for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.