Poorer subjective sleep quality is associated with greater glycemic variability in nondiabetic African American pregnant women
In a secondary analysis of 55 nondiabetic African American pregnant women (16-22 weeks gestation), poorer subjective sleep quality (measured by PSQI) was significantly associated with higher glucose SD (B = 0.42, 95% CI [0.07, 0.76]), higher MAGE (B = 1.10, 95% CI [0.30, 1.91]), and greater CV (B = 0.44, 95% CI [0.12, 0.75]). No objective sleep dimensions (Fitbit Inspire 2) were significantly associated with glycemic outcomes.
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Poorer subjective sleep quality is associated with greater glycemic variability in nondiabetic African American pregnant women The current body of evidence comprises 1 study. EvidenceHub rates the overall confidence at 34/100 (low).
The Claim
Poorer subjective sleep quality is associated with greater glycemic variability in nondiabetic African American pregnant women
This conclusion is most relevant to: Nondiabetic African American pregnant women (16-22 weeks gestation), aged 18-42, BMI 24-45 kg/m2, singleton pregnancies.
What the Research Shows
The conclusion draws on 1 linked study. Highlights from the cited literature:
- ▸Sleep Quality and Glycemic Variability Among Nondiabetic African American Pregnant Women. (Journal of obstetric, gynecologic, and neonatal nursing : JOGNN, 2026) —
How It Works
The proposed biological pathway:
- ▸Subjective sleep quality assessed via PSQI
- ▸Glycemic variability measured via continuous glucose monitoring
- ▸Between-person regression and within-person mixed-effects models
- ▸Poorer subjective sleep quality associated with higher glycemic variability
Who Might Benefit
Evidence fit by population:
- ▸Nondiabetic African American pregnant women (16-22 weeks gestation), aged 18-42, BMI 24-45 kg/m2, singleton pregnancies
Recommended Dose
N/A
Limitations & Caveats
Important context when interpreting this evidence:
- ▸Secondary analysis of baseline data from an RCT, not a prospective cohort
- ▸Small sample size (N=55) limits generalizability
- ▸Objective sleep measured with consumer-grade Fitbit, not validated for pregnancy
- ▸Potential residual confounding from unmeasured factors
Frequently Asked Questions
What is the main finding of this study?▼
Poorer subjective sleep quality (higher PSQI scores) was associated with greater glycemic variability (higher glucose SD, MAGE, and CV) in nondiabetic African American pregnant women.
Did objective sleep measures show any association with glycemic outcomes?▼
No, none of the objective sleep dimensions (duration, efficiency, timing, regularity) measured by Fitbit Inspire 2 were significantly associated with glycemic outcomes.
What population was studied?▼
55 nondiabetic African American pregnant women between 16-22 weeks gestation, aged 18-42, with BMI 24-45 kg/m2.
What are the implications for prenatal care?▼
Assessing perceived sleep quality may help identify early pregnancy metabolic risk and could be a modifiable target for interventions to reduce glycemic variability.
References
- 1.Irsheed GA, Genao N, Siwakoti L, Steffen A, Ackerman W, Quinn L, Borbas L, Alameda G, Maganuru R, Nazeer N, Virmani A, Burke L, Balserak BI. “Sleep Quality and Glycemic Variability Among Nondiabetic African American Pregnant Women..” Journal of obstetric, gynecologic, and neonatal nursing : JOGNN, 2026. PMID: 42648704 DOI: 10.1016/j.jogn.2026.08.001