Herbs · Ashwagandha

Standardized ashwagandha extracts improve sleep quality in clinical trials

Clinical trials with standardized ashwagandha extracts have shown improvements in sleep quality and mood parameters, along with reductions in stress-related biomarkers. The review highlights these effects as part of ashwagandha's adaptogenic and neuroimmune regulatory properties.

1 min read•Updated Jul 7, 2026•0 RCTs•View structured evidence →
Evidence Score32/100
Human RCT☆☆☆☆☆
Meta-analysis☆☆☆☆☆
Mechanism☆☆☆☆☆
Safety☆☆☆☆☆
Confidencelow

This article is automatically generated from the structured evidence profile behind the claim above. Scores reflect the quality and quantity of available research, not clinical advice.

Standardized ashwagandha extracts improve sleep quality in clinical trials The current body of evidence comprises 1 study. EvidenceHub rates the overall confidence at 32/100 (low).

The Claim

Standardized ashwagandha extracts improve sleep quality in clinical trials

This conclusion is most relevant to: Human subjects in clinical trials (specific demographics not detailed in abstract).

What the Research Shows

The conclusion draws on 1 linked study. Highlights from the cited literature:

  • ▸Ashwagandha as an Adaptogenic Herb: A Comprehensive Review of Immunological and Neurological Effects. (Cureus, 2025) —

How It Works

The proposed biological pathway:

  • ▸Modulation of hypothalamic-pituitary-adrenal (HPA) axis
  • ▸Inhibition of NF-κB and induction of Nrf2 activation
  • ▸Effects on GABAergic signaling
  • ▸Result: Anti-inflammatory, antioxidant, and anxiolytic actions leading to improved sleep

Who Might Benefit

Evidence fit by population:

  • ▸Human subjects in clinical trials (specific demographics not detailed in abstract)

Limitations & Caveats

Important context when interpreting this evidence:

  • ▸Heterogeneity in the preparation of extracts across studies
  • ▸Small sample sizes and variability in endpoints
  • ▸Possible funding-related biases

References

  1. 1.Jamnekar PP, Dehankar TJ, Bedre RV, Dharan BG, Agravat B, Agravat H. “Ashwagandha as an Adaptogenic Herb: A Comprehensive Review of Immunological and Neurological Effects..” Cureus, 2025. PMID: 41356880 DOI: 10.7759/cureus.96183
Disclaimer: This article is auto-generated from structured research data for educational purposes only and is not medical advice. Evidence scores reflect the quality and quantity of available research, not clinical recommendations. Always consult a healthcare professional before starting any supplement or intervention.