Both VL-G-A57 (Rhodiola, holy basil, Schisandra chinensis) and VL-G-E12 (full-spectrum ashwagandha) improve sleep quality in individuals with high stress
In a 60-day randomized, double-blind, placebo-controlled trial involving 186 participants with high stress, both VL-G-A57 and VL-G-E12 significantly improved sleep quality as measured by the Pittsburgh Sleep Quality Index (PSQI) compared to placebo (VL-G-A57: p=0.0008, VL-G-E12: p<0.0001). Restorative Sleep Questionnaire-Weekly (RSQ-W) results also showed significant improvements in both active groups versus placebo (p<0.0001).
Evidence Score
Study Evidence
Study 1. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
observationalMcKinney E, Stewart J, Kewalramani R, Singh S · Trials (2026)
Result:
Mechanism Graph
Limitations
- ⚠Dose information not provided in abstract
- ⚠Mechanism of action not directly measured in this study
- ⚠Short-term duration (60 days) limits long-term conclusions
Frequently Asked Questions
What is VL-G-A57?▼
VL-G-A57 is a plant-based adaptogen formula containing Rhodiola rosea, holy basil (Ocimum sanctum), and Schisandra chinensis.
What is VL-G-E12?▼
VL-G-E12 is a full-spectrum ashwagandha (Withania somnifera) root formula.
How was sleep quality measured in this study?▼
Sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI) and the Restorative Sleep Questionnaire-Weekly (RSQ-W).
Did both formulas improve sleep?▼
Yes, both VL-G-A57 and VL-G-E12 significantly improved sleep quality and restorative sleep compared to placebo at day 60.
Products
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References
- 1.McKinney E, Stewart J, Kewalramani R, Singh S. "Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.." Trials, 2026. PMID: 41656269 DOI: 10.1186/s13063-026-09495-9